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NSW The SEPSIS KILLS program

NSW The SEPSIS KILLS program has been incrementally introduced in NSW acute public health facilities since 2011. The program has raised sepsis awareness, improved care, and reduced preventable harm from sepsis in adults, children, mothers and babies across NSW. Resources includes information on the Sepsis Kills Program, Sepsis pathways, Education, Sepsis awareness, and key publications.

QLD Health, Clinical Excellence Queensland

With rates of sepsis increasing in Queensland, Clinical Excellence Queensland is working with key stakeholders to improve early recognition and treatment of sepsis in an effort to reduce its devastating impact on families and our communities. For information on adult sepsis, paediatric sepsis, pathways and resources, prevalence of sepsis, recognition and treatment, signs and symptoms, pharmacy and primary care program and post sepsis care.

VIC Safer Care Sepsis (for EDs and UCCs)

Together with healthcare staff and consumers have developed resources for emergency departments and urgent care centres to support early recognition and management of sepsis. For more on clinical pathways and implementation.

VIC Safer Care, Melbourne Health and Victorian Comprehensive Cancer Centre

The Peter MacCallum Cancer Centre developed a whole-of-hospital sepsis pathway in February 2013 which was later adapted for cancer services at Melbourne Health in June 2015 with positive patient outcomes. Through its innovation project, Melbourne Health again adapted the Peter MacCallum Cancer Centre’s sepsis pathway, this time implementing it across the Royal Melbourne Hospital to ensure all patients were receiving the highest quality of care every single time. In December 2020, due to its success, the Better Care Victoria Innovation Fund supported the scaling and spreading of this innovation project.

Key Outcomes included:

  • Developed an evidence-based sepsis clinical pathway that has been used in more than 700 episodes of care
  • Halved the rate of death due to sepsis
  • Reduced ICU admissions by 65.4 per cent
  • Reduced the time from diagnosis to administration of antibiotic treatment by 51.9 per cent
  • Decreased patients’ hospital length of stay by 42.9 per cent

Northern Territory Health

Sepsis information and resources including:

Sepsis pathways for use in all settings incorporate evidence-based risk criteria to help clinicians recognise sepsis early and support early escalation of care and management.​

  • Sepsis guidelines to support the sepsis pathways and provide further guidance in:
    • Best practice and a consistent approach across all NT health services for early sepsis recognition and management.
    • Where sepsis is suspected, empower staff to escalate care to clinicians experienced in recognising and managing sepsis.
    • Engaging senior medical staff in sepsis recognition and management of patients.
    • Supporting the provision of education and information for patient and carers.
  • For acute care:
    • Adult acute care – NT Health sepsis recognition and management guideline
    • Paediatric acute care – NT Health sepsis recognition and management guideline
  • For primary health care:
    • Adult primary health care – NT Health sepsis recognition and management guideline
    • Paediatric primary health care – NT Health sepsis recognition and management guideline
  • The Remote Health Atlas or Primary Health Network sites have updated sepsis guidelines to align with NT Health to ensure consistency of practice across the NT.
  • Sepsis e-learning module ‘Sepsis Introduction’ is available to all health professionals to better understand what sepsis is, its impact in the NT, how to identify and manage sepsis, and with the use of case studies, assists in applying the sepsis pathways into practice.
  • Septris 2.0 is a mobile-accessible, case-based, online game launched worldwide and developed for hospital-based medical and surgical, intensive care and emergency department physicians and nurses for treating Sepsis.

Australian Commission on Safety and Quality in Health Care (‘the Commission’)

In 2019, following lobbying by The George Institute’s Sepsis Australia Program a one off funding allocation was provided by the Australian Government Department of Health to support implementation of the Stopping Sepsis National Action Plan recommendations under a National Sepsis Program led collaboratively by The George Institute’s Sepsis Australia and the Commission which was completed in June 2022 at the launch of the national Sepsis Clinical Care Standard resulting delivery of the following projects:

  • Project 1: Epidemiology of sepsis report
  • Project 2: National retrospective medical record review
  • Project 3: Sepsis trigger tools systematic review
  • Project 4: Materials to support implementation of National Safety and Quality Health Service Standards (NSQHS)
  • Project 5: Revision of the Antimicrobial Stewardship Clinical Care Standard
  • Project 6: Sepsis Clinical Care Standard
  • Project 7: Public awareness campaign
  • Project 8: Sepsis Survivorship

In 2022-23, following further lobbying by The George Institute’s Sepsis Australia Program a second one off funding allocation was provided by the Australian Government Department of Health and Aging to support implementation of additional Stopping Sepsis National Action Plan recommendations under a National Sepsis Program Extension led collaboratively by The George Institutes Sepsis Australia and the Commission to deliver projects on:

  • Improving recognition of sepsis for First Nations people
  • Targeted national public awareness campaign
  • Education and training resources for health services
  • Coordinated sepsis care and post sepsis support for sepsis survivors, their families, and families bereaved by sepsis
  • National plan for sepsis data collection and tools for quality improvement

National Sepsis Clinical Care Standard (SCCS)

A cornerstone recommendation of the Sepsis Australia Stopping Sepsis National Action Plan was the SCCS, which aims to ensure sepsis is recognised early and patients receive coordinated, best-practice care so that the risk of death or ongoing morbidity is reduced. This includes timely recognition of sepsis, early and appropriate antimicrobial therapy and continuity of care from the acute setting through to discharge and survivorship. The SCCS is a component of the Australian Health Service Safety and Quality Accreditation Scheme and comprises:

  • Seven quality statements describing the care that should be provided
  • Guidance for consumers, clinicians, and healthcare services
  • Implementation support services including a self-assessment tool for health services to undertake gap analysis
  • Quality improvement clinical indicator monitoring tool
  • Guidance on the use of antimicrobials, lactate testing, and discharge planning

Society of Critical Care Medicine Surviving Sepsis Campaign

Initiated in 2002 the campaign has published four editions of evidence-based guidelines, implementation of a performance improvement program, and analysis and publication of data from more than 30,000 patient charts collected from around the world. The three key phases underpinning  guideline development are:

Phase I:  Development of Awareness of Scope of the Problem

Phase II:  Development and Publication of Guidelines

Phase III:  Guideline Implementation, Behaviour Change, and Data Collection

In 2023/24, the SSC Guidelines are undergoing review with publication expected early 2025. See resources to access current sepsis guidelines and bundles for adults, paediatrics and associated tools and education.

World health organization (who)

To improve clinical outcomes, patients with sepsis require effective systems of care, which include key functions such as early recognition, resuscitation, targeted antimicrobial therapy, source control, intensive monitoring and detection of clinical deterioration, and continuing prevention of organ failure and complications.  Integrated Clinical Care for Sepsis is being progressed by the Clinical Service and Systems Unit which is supporting the delivery of patient centred care for sepsis patients through the system planning and pathways to care toolkit.

WHO – Guidelines on the Clinical Management of Sepsis

WHO is developing guidance using the best evidence to help patients and the healthcare workers looking after them. The guidance will focus on making global recommendations for early recognition, initial resuscitation, and the early treatment of sepsis during which periods patients are most vulnerable. The recommendations support to Member States to develop and implement national programs for the management of sepsis in adults and children. The wide intended audience includes health care workers (health professionals including doctors, nurses, intensivists/critical care staff, ambulance staff), policy-makers, their expert advisers and technical/ program staff at organisations involved in the management of adults or children with sepsis. Recommendations will be published as WHO guidelines, and will include tools to support implementation.

Resources for health professionals